Monday, 8 December 2014

Sodium Citrate


The three essentials and what they have in common. By Thomas Herd

You’ve just woken up and hopped in the shower and you think to yourself , “what keeps this shampoo thick?”. The answer is more than likely sodium citrate. The citrus taste in the powerade you downed after basketball or the morning after a long night also probably came for the additive sodium citrate. When you get home from school and take out some frozen food and cook it, the reason it’s still fresh has to do with the actions of preservatives, like sodium citrate(5). Shampoo, sports drinks, and ready to heat meals, what would we do without them.
Sodium citrate, referred to in the IUPAC convention as trisodium;2-hydroxypropane-1,2,3-tricarboxylate, is consumed by people everyday(7). This consumption is allowed because using all the current information sodium citrate is considered to be completely safe. It is not believed to a carcinogen. It is not believed to harm the environment. It is also not believed to be bio accumulative(8). However, just like anything else, if you have enough of it, it can kill you. The lethal dose that killed 50% of mice is 6mmol/kg and in rats is 5.5mmol/kg(5). However if you are taking sodium citrate pills for stomach relief there can be some serious side effects. These side effects range from swelling to seizures(1).
Sodium citrate is made from the chemical processing of citric acid. When you mix sodium carbonate with citric acid a reaction occurs that causes a fizzing reaction. When the fizzing ends the solution is allowed to evaporate. What is left is sodium citrate(7).
You come across is everyday and it is neither bad for you, or necessarily good for you. It is simply a chemical making product making your everyday products possible.

References
(1) citric acid and sodium citrate health encyclopedia norris cotton center. Retrieved on Nov. 14, 2014 from                    http://cancer.dartmouth.edu/pf/health_encyclopedia/d03952a1

(2)Disappearing Milk and Perfectly Melting Cheese. Retrieved on Nov.14, 2014 from                       http://doctorbrookschemistry.net/disappearingmilk/

(3)GRAS substnaces (SCOGS database). Retrieved on Nov.14, 2014 from                                http://www.fda.gov/Food/IngredientsPackagingLabeling/GRAS/SCOGS/ucm260742.htm

(4)Lofty,W et al (2006) Citric Acid Production by a Novel Aspergillus Niger Isolate: II. Optimization of Process          Parameters Through Statistical Experimental Designs; Biosource Technology 98.(2007) 3470-3477

(5)O'Neil, M.J., (Ed.). (2006). The Merck Index: An Encyclopedia of Chemicals, Drugs, and Biologicals (14th ed.).             NJ: Merck

(6)Osol, A. and J.E. Hoover, et al. (eds.). Remington's Pharmaceutical Sciences. 15th ed. Easton, Pennsylvania: Mack       Publishing Co., 1975., p. 802

(7)Sodium Citrate – PubChem. Retrieved on Nov.14, 2014 from                                               http://pubchem.ncbi.nlm.nih.gov/compound/6224?from=summary#section=Physical-Description

(8)Sodium Citrate, Skin Deep Cosmetics Database Environemtal Working Group. Retrieved on Nov. 17, 2014      from http://www.ewg.org/skindeep/ingredient/706027/SODIUM_CITRATE/

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